Effect of sodium hyaluronate-arboxycellulose membrane (Seprafilm®) on postoperative small bowel obstruction: A meta-analysis
نویسندگان
چکیده
BackgroundThis meta-analysis was performed to evaluate the effect of Seprafilm® on postoperative small bowel obstruction.MethodsA literature search conducted in PubMed and EMBASE databases through August 2020. The pooled risk ratios as well corresponding 95% confidence intervals were calculated using RevMan 5.3 software.ResultsA total 9 clinical control trials involving 4,351 patients (2,123 group 2,228 group) included. overall analysis showed that ratio 0.45 (95% interval = 0.34–0.60; P < .00001), indicating obstruction can be significantly decreased by application Seprafilm®. Similarly, an obvious reducing rate also shown subgroup analyses population (adult participants), study design (randomized or nonrandomized study), region (Japan Korea), follow-up duration (2 years 5 years), sheet number (1 >1 sheet).ConclusionIn conclusion, use is beneficial for decreasing obstruction.
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ژورنال
عنوان ژورنال: Surgery
سال: 2021
ISSN: ['0039-6060', '1532-7361']
DOI: https://doi.org/10.1016/j.surg.2020.12.004